104-19 ScienCell 重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19
ScienCell 研究實(shí)驗(yàn)室(ScienCell)是一家生物技術(shù)公司,其使命是實(shí)驗(yàn)和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類和動物細(xì)胞,細(xì)胞培養(yǎng)基和試劑,培養(yǎng)基添加因子,細(xì)胞來源的RNA,cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量,實(shí)現(xiàn)細(xì)胞的能力,打擊人類退化性疾病為目的研究和開發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國加利福尼亞州圣地亞哥,公司成立于1999年。
北京諾博萊德作為ScienCell品牌的特約經(jīng)銷商,為客戶提供,正規(guī)進(jìn)口,貨期穩(wěn)定,折扣好的服務(wù)標(biāo)準(zhǔn)。
104-19 ScienCell重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19,產(chǎn)品簡介:
產(chǎn)品品牌; ScienCell
產(chǎn)品貨號:104-19
產(chǎn)品名稱:104-19 ScienCell重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19
產(chǎn)品規(guī)格:5ug
ScienCell提供純化的、高質(zhì)量的生長因子,為您的研究助力。一些專門的信號分子,在細(xì)胞的增殖和分化中發(fā)揮核心作用。只有高純度的因子才能實(shí)現(xiàn)信號通路的高強(qiáng)度活化。 ScienCell提供的生長因子具有以下特性:高活性,少量的蛋白即有很強(qiáng)效應(yīng);高純度,污染物少,干擾小。
104-19 ScienCell重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19, 產(chǎn)品說明:
成纖維細(xì)胞生長因子19(FGF-19)屬于大型FGF家族,至少有23個成員。然而,FGF-19與FGF-21和FGF-23一起屬于非典型FGF的亞家族,其中缺乏傳統(tǒng)的肝素結(jié)合基序。因此,它的信號轉(zhuǎn)導(dǎo)是由輔因子介導(dǎo)的?Klotho與FGFRs 1c、2c和3c相互作用時。有趣的是,FGF-19可以在沒有 ?克洛托。FGF-19調(diào)節(jié)代謝過程,包括膽汁酸,脂質(zhì)和葡萄糖穩(wěn)態(tài),以及肝細(xì)胞增殖。向小鼠施用重組FGF-19可降低膽固醇7-α-羥化酶(CYP7A1)的表達(dá),這是肝臟膽汁酸生物合成途徑的限速步驟。
Fibroblast growth factor 19 (FGF-19) belongs to the large FGF family which has at least 23 members. However, FGF-19, along with FGF-21 and FGF-23, belongs to a subfamily of atypical FGFs where it lacks a conventional heparin-binding motif. Therefore, its signal transduction is mediated by the cofactor ?Klotho when interacting with FGFRs 1c, 2c and 3c. Interestingly, FGF-19 can interact directly with FGFR4 in absence of ?Klotho. FGF-19 regulates metabolic processes including bile acid, lipid and glucose homeostasis, as well as hepatocyte proliferation. Administration of recombinant FGF-19 to mice decreased cholesterol 7-alpha-hydroxylase (CYP7A1) expression, the rate limiting step in bile acid biosynthesis pathway in the liver.
ScienCell生長添加物產(chǎn)品訂購信息:
102-01 重組人干細(xì)胞因子 rhSCF,Recombinant Human Stem Cell Factor 2ug
102-02 重組人粒細(xì)胞集落刺激因子 rhG-CSF,Recombinant Human Granulocyte Colony Stimulating Factor 2ug
102-03 重組人粒細(xì)胞巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Granulocyte Macrophage Colony Stimulating Factor 5ug
102-09 重組人巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Macrophage Colony Stimulating Factor 2ug
103-01 重組人腫瘤壞死因子-alpha rhTNF-α,Recombinant Human Tumor Necrosis Factor-alpha 10ug
103-01H 重組人腫瘤壞死因子-alpha,rhTNF--His,Recombinant Human Tumor Necrosis Factor-alpha, His 10ug
103-01v 重組人腫瘤壞死因子-alpha,Variant rhTNF-α variant,Recombinant Human Tumor Necrosis Factor-alpha Variant 10ug
103-04 重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor 5ug
103-08 重組人制瘤素-M227a.a. rhOSM,Recombinant Human Oncostatin-M 227a.a. 2ug
103-08T 重組人制瘤素-M209a.a.,Recombinant Human Oncostatin-M209a.a 2ug
103-09 重組人血管生成抑制因子K1-3 rhAngiostatin K1-3,Recombinant Human Angiostatin K1-3 10ug
103-12 重組人血管內(nèi)皮抑制素 rhEndostatin,Recombinant Human Endostatin 20ug
104-01 重組人成纖維細(xì)胞生長因子-acidic rhaFGF,Recombinant Human Fibroblast Growth Factor-acidic 10ug
104-02 重組人成纖維細(xì)胞生長因子-basic rhbFGF,Recombinant Human Fibroblast Growth Factor-basic 10ug
104-07 重組人角質(zhì)細(xì)胞生長因子 rhKGF-1,Recombinant Human Keratinocyte Growth Factor-1 2ug
104-09 重組人成纖維細(xì)胞生長因子-9 rhFGF-9,Recombinant Human Fibroblast Growth Factor-9 5ug
104-10 重組人角質(zhì)細(xì)胞生長因子-2 rhKGF-2,Recombinant Human Keratinocyte Growth Factor-2 5ug
104-19 重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19 5ug
104-21 重組人成纖維細(xì)胞生長因子-21 rhFGF-21,Recombinant Human Fibroblast Growth Factor-21 5ug
105-01 重組人胰島素生長因子-1 rhIGF-1,Recombinant Human IGF-I 20ug
105-01B 重組人DES(1-3)胰島素生長因子-1 rhIGF-BP3,Recombinant Human DES (1-3) IGF-1 20ug
105-01B3重組人胰島素生長因子-BP3,Recombinant Human IGF-BP3 5ug
105-03 重組人longR3胰島素生長因子-1 rhLR3IGF-1,Recombinant Human Long R3 Insulin-like Growth Factor-1 20ug
105-04 重組人表皮生長因子 rhEGF,Recombinant Human Epidermal Growth Factor, 100 ug 100ug
105-05 重組人血管內(nèi)皮生長因子-165 rhVEGF165,Recombinant Human VEGF165 2ug
106-06 重組人干擾素γ rhIFN-γ,Recombinant Human Interferon-gamma 20ug
107-04 重組人神經(jīng)營養(yǎng)蛋白-4 rhNT-4,Recombinant Human Neurotrophin-4 2ug
107-08 重組人纖毛神經(jīng)營養(yǎng)因子 rhCNTF,Recombinant Human Ciliary Neurotrophic Factor 5ug
107-10 重組人神經(jīng)調(diào)節(jié)蛋白 rhBTC,Recombinant Human NRG-1 EGF-like domain 10ug
107-11 重組人ErbB3片段 rhErbB3-f,Recombinant Human ErbB3 Fragment 5ug
107-12 重組人β動物纖維 rhBTC,Recombinant Human Betacellulin 5ug
108-02 重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 2ug
108-04 重組人骨形成蛋白-4 rhBMP-4,Recombinant Human Bone Morphogenetic Protein-4 2ug
108-07 重組人骨形成蛋白-7 rhBMP-7,Recombinant Human Bone Morphogenetic Protein-7 2ug
108-08 重組人骨保護(hù)素 rHuOPG-Fc,Recombinant Human Osteoprotegerin/Fc Chimera 10ug
108-09 重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN 5ug
301-01 重組人生長激素 rhGF,Recombinant Human Growth Hormone 20ug